CLINICAL MEDICINE
Tenth All-Russian
young researchers
"Man and his health"
Saint Petersburg
The Russian Academy of Sciences
Scientific Council of the Russian Academy of Sciences for Physiological Sciences
St. Petersburg Scientific Council on Problems
biology and medicine
Federal Agency of Education of the Russian Federation
St. Petersburg State University
Faculty of Medicine
Russian Physiological Society
them. I.P. Pavlova
St. Petersburg City Palace of Youth Creativity
FUNDAMENTAL
AND
CLINICAL MEDICINE
Tenth All-Russian
biomedical conference
young researchers
"Man and his health"
Chairman S.V. Petrov, Doctor of Medical Sciences, Professor
Deputy Chairman N.P. Veselkin, corresponding member. RAS
O.V. Fionik, Ph.D., Associate Professor
Members of the organizing committee E.K. Ailamazyan, Academician of the Russian Academy of Medical Sciences
Yu.V. Natochin, Academician of the Russian Academy of Sciences
N..N. Petrova, Doctor of Medical Sciences
Program Committee A.V. Balakhonov, Ph.D., Associate Professor
L.G. Magazanik, corresponding member. RAS
YES. Niauri, Doctor of Medical Sciences, Professor
A.G. Obrezan, Doctor of Medical Sciences, Professor
N.N. Petrova, Doctor of Medical Sciences
O.V. Fionik, Ph.D., Associate Professor P.K.
L.P. Churilov, Ph.D., Associate Professor
S.D. Sheyanov, Doctor of Medical Sciences, Professor
A.N. Shishkin, Doctor of Medical Sciences, Professor
M.V. Erman, Doctor of Medical Sciences, Professor
PC. Yablonsky, Doctor of Medical Sciences
Editorial board I.P. Mavidi, Ph.D.
E.R. Khalitova
RELATIONSHIP OF CLINICAL
AND CYTOGENETIC DISORDERS
IN CEREBRAL PALSY
D.V. Abdullatypova, class. hord.
Kazan State Medical University,
Department of Neurology, Neurosurgery with a course medical genetics. Kazan, Russia
Objective: to study the relationship between clinical and cytogenetic disorders in cerebral palsy (CP).
Research material. 71 children with various forms cerebral palsy and 40 healthy individuals. The study included children with intact intelligence studying at a specialized boarding school for children with cerebral palsy. All patients were divided into clinical forms of the disease: hyperkinetic – 13 people. (18.3%), hemiparetic – 25 people. (35.2%) and spastic diplegia – 33 people. (46.5%).
Research methods: 1) clinical and neurological, including a score of the severity of 22 clinical indicators of movement disorders, each of which was scored from 0 to 5 points; 2) micronucleus test, with the study of 20,000 red blood cells in a peripheral blood smear from each patient and identifying the number of red blood cells with micronuclei (EM), expressed as a percentage; 3) statistical.
Results. A score assessment of the severity of clinical manifestations of cerebral palsy revealed that the most severe changes in self-care, motor deficits, and sensory functions are significantly more often determined in children with the hyperkinetic form of cerebral palsy, compared with other forms (p
The average values of EM in all forms of cerebral palsy significantly exceeded the spontaneous level of cytogenetic disorders in the control group 0.21% and 0.08%, respectively (p
The preliminary data obtained suggest that girls suffer more severely from cerebral palsy, whereas it is known that the disease is more common in boys. Sex differences are clearly visible in diseases of a multifactorial nature. Since with multifactorial inheritance the severity of the disease in the rarely affected sex is more severe, with a certain degree of probability cerebral palsy can be attributed to a pathology with polygenic inheritance. Of course, these proposals require additional research in this direction.
FEATURES OF PERFORMANCE OF SPECIFIED MOTOR ACTIONS WHEN LEFT-HANDERS AND RIGHT-HANDERS PERCEIVE FEEDBACK OF DIFFERENT CHARACTER
A.P. Abramova, student
Tver Gymnasium No. 44. Tver, Russia
Most human activities are associated with the perception and processing of information. Considering the presence of dominance of one of the hemispheres, a problem arises: what are the features of motor actions when perceiving verbal or formalized information in people with different leading hemispheres.
Purpose: to analyze the difference in the performance of precision movements when left-handers and right-handers perceive information feedback of a verbal and formal nature.
The study is based on the kinematometry method, which makes it possible to quantify muscle-joint sensitivity. The study included two series of experiments. First episode. Reproduction accuracy was recorded for left- and right-handers right forearm at a given angle of 45 degrees on a horizontal kinematometer. The position of the forearm is fixed at a given angle under visual control. Then the subject with his eyes closed reproduces the given angle 5 times at following conditions: a) without informing the subject of the result of the action performed; b) with communication to the subject of the result of the completed action in verbal form, using words "more"- when the specified angle is exceeded, "less"- when not reaching the specified angle and "exactly"- when accurately reproducing a given angle; c) with communication to the subject of a specific (formalized) result of the action performed - for example, “42 degrees”. Second series The experiment included repetition of these experiments, but when reproduced by left-handers and right-handers with the movement left forearm at a given angle of 45 degrees.
The results of two series of experiments show that right-handers and left-handers are equally poor at performing precise movements based on proprioceptive information, and feedback in the form of a subjective sensation of muscle tension is insufficient to correct motor action. The presence of interhemispheric functional asymmetry of the sensory type determines the difference in the perception of verbal and formalized information feedback by left-handers and right-handers: when operating with the dominant hand, right-handers perceive verbal information better, and left-handers perceive formalized information better. The degree of formalization of feedback affects the accuracy of correction when performing given motor actions: the higher the level of formalization of feedback, the more accurate the subsequent action performed.
INFLUENCE OF SOME RISK FACTORS OF EARLY DYSONTOGENESIS ON MEMORY DEVELOPMENT IN HIGH SCHOOL STUDENTS
M.A. Abramova, student.
Pomeranian State University
them. M.V. Lomonosov, Faculty of Psychology, Department of Psychology. Arkhangelsk, Russia
The need to analyze the causes of possible deviations and organize individual correctional assistance for high school students during the period of their development is most relevant, because occur in early adolescence important processes associated with memory restructuring (Leontyev A.N., 1931, Rean A.A., 2003). The purpose of our work is to identify the influence of risk factors for early dysontogenesis on memory development in children 15-16 years old.
During scientific work 24 people aged 15-16 years (12 boys and 12 girls) studying at high school No. 50 in Arkhangelsk and did not have a history of severe neurological disorders. At the first stage of the study, the most common risk factors for early dysontogenesis in high school students were identified using a questionnaire developed at the Research Institute of Age-Related Physiology of the Russian Academy of Education. At the second stage, methods were selected that made it possible to comprehensively assess the psychophysiological development of memory in an individual child: the “10 words” test (auditory short-term memory), the Bernstein test “9 geometric shapes"(short-term visual memory), a method of reproducing differently perceived words (leading type of memory).
A study of the level of psychophysiological development of children 15-16 years old indicates that the majority of high school students have a volume of short-term auditory (75.00±1.46% of children) and visual memory (83.33±1.54% of children) that corresponds to age standards. For the majority of adolescent children, the leading types of memory are combined (41.67±1.09) and visual (20.83±0.77).
A survey of parents of high school students revealed that 83.33±1.54% of children have risk factors in early development: toxicosis of the first half of pregnancy, maternal age, artificial feeding of the child from birth, taking medications during pregnancy, maternal morbidity during pregnancy .
INTERNATIONAL MEDICAL-BIOLOGICAL
SCIENTIFIC CONFERENCE OF YOUNG SCIENTISTS
"BASICAL SCIENCE AND CLINICAL MEDICINE"
(Annual All-Russian Conference "Man and His Health")
20 April 2019 year will take placeXXII International medical and biological scientific conference of young researchers " Basic Science and clinical medicine. Man and his health"
Location: St. Petersburg State University, Twelve Collegium Building (University Embankment 7-9), Assembly Hall, Petrovsky Hall.
Schoolchildren, students, residents, graduate students, young scientists (under the age of 35) are invited to participate. full years). Works are accepted on a wide range of problems in all branches of clinical and preventive medicine, as well as morphology, physiology, pathology, pharmacology, biophysics, bioinformatics, biomedical cybernetics, biochemistry, and genetics. Sections are devoted to biomedicine and clinical medicine, and there is a special seminar under the auspices of the International Society of Pathophysiologists. The purpose of the conference is to attract young researchers to solve pressing problems of modern science, integration higher education and fundamental science. Oral and poster presentations will be selected from the submitted works. Abstracts of the conference reports will be published in the ongoing publication of St. Petersburg State University “Fundamental Science and Clinical Medicine” (Fundam. Nauka Klin. Med.), ISSN 2221-5654, volume 22.
Abstracts are accepted until March 1, 2019 and can only be submitted through automatic system registration of participants and submission of materials.
April 14, 2018 The XXI International Medical and Biological Scientific Conference of Young Researchers “Basic Science and Clinical Medicine. Man and his health."
Schoolchildren, students, residents, graduate students, and young scientists (under the age of 35) are invited to participate. Works are accepted on a wide range of problems in all branches of clinical and preventive medicine, as well as morphology, physiology, pathology, pharmacology, biophysics, bioinformatics, biomedical cybernetics, biochemistry, and genetics. Sections are devoted to biomedicine and clinical medicine, and a special seminar is provided.
Location: St. Petersburg State University, Universitetskaya embankment. 7-9, Assembly Hall, Petrovsky Hall.
April 22, 2017 The XX International Medical and Biological Scientific Conference of Young Researchers “Basic Science and Clinical Medicine. Man and his health."
Venue: St. Petersburg State University, Twelve Collegium Building (University Embankment 7-9), Assembly and Petrovsky Halls.
Schoolchildren, students, residents, graduate students, and young scientists (under the age of 35) are invited to participate. Works are accepted on a wide range of problems in all branches of clinical and preventive medicine, as well as morphology, physiology, pathology, pharmacology, biophysics, bioinformatics, biomedical cybernetics, biochemistry, and genetics.
The purpose of the conference is to attract young researchers to solve current problems modern science, integration of higher education and fundamental science. Oral and poster presentations will be selected from the submitted works.
Abstracts will be accepted until March 1, 2017 and can be submitted only through an automatic system for registering participants and submitting materials.
Abstracts submitted in violation of these rules cannot be accepted. After reviewing the abstracts by the editorial board, the authors will receive a notification about participation in the conference and about the oral or poster form of the report.
Email: This address Email protected from spam bots. You must have JavaScript enabled to view it.
NB! Email address Email is indicated only for questions, abstracts by email. mail cannot be accepted.
Abstracts of the international medical and biological scientific conference “Basic Science and Clinical Medicine” are available for download:
On April 23, 2016, St. Petersburg State University hostedXIX International medical and biological conference of young researchers "Basic science and clinical medicine. Man and his health."
The conference was attended by more than 500 young researchers and leading scientists from 174 scientific, educational and medical organizations 75 cities in Russia, as well as Belarus, Great Britain, Vietnam, Jordan, Kazakhstan, China, Moldova, Namibia, Nigeria, Ukraine, Uzbekistan, Finland, France, Croatia.
At the conference, 36 oral reports were heard and 174 poster reports were presented.
In the ongoing publication Basic Science and Clinical Medicine: Abstracts XIX International Medical and biological conference of young researchers. - St. Petersburg: St. Petersburg State University Publishing House, 2016. - 694 p. [Fundam. science wedge. honey. - 2016. - vol. 19. - p. 1–694] published abstracts of 586 works by more than 900 young researchers and lectures by leading scientists.
Following the results of the conference, an interuniversity jury with the participation of representatives of the Russian Academy of Sciences, medical and pharmaceutical universities of St. Petersburg, scientific and professional medical and natural science societies, the Palace of Youth Creativity and the medical book publishing house "ELBI-SPb" awarded diplomas and prizes to the best works.
XVIII International Medical and Biological Conference of Young Researchers “Basic Science and Clinical Medicine. Man and his health”, dedicated to the twentieth anniversary of the Faculty of Medicine of St. Petersburg State University
On April 18, 2015, the XVIII International Medical and Biological Conference of Young Researchers was held at St. Petersburg State University, in the building of the Twelve Collegiums
“Basic science and clinical medicine. Man and his health”, dedicated to the twentieth anniversary of the Faculty of Medicine of St. Petersburg State University, at which young scientists presented works on current fundamental and applied issues of experimental, clinical, preventive medicine and related biomedical sciences.
This year, the conference was attended by more than 500 young researchers and leading scientists from almost 200 organizations in 75 cities of Russia, as well as Bangladesh, Belarus, Israel, Kazakhstan, Moldova, Mongolia, Namibia, Serbia, the USA, Ukraine, Uzbekistan, Croatia, Jamaica, Japan.
At the conference itself, 35 oral reports were heard and more than 160 poster reports were presented, in the ongoing publication Fundamental Science and Clinical Medicine - Man and His Health: Abstracts of the XVIII International Medical and Biological Conference of Young Researchers - 540 works by 882 young researchers and lectures by leading scientists.
Following the results of the conference, the winners were awarded diplomas of various denominations in the categories of oral and poster presentations on clinical and medical-biological topics, as well as special prizes and diplomas from scientific and professional societies - the St. Petersburg branch of the International Society of Pathophysiologists (ISP), the St. Petersburg City Palace of Creativity Young, publishing house "Elbi-SPb", Bekhterevsky Psychiatric Society, St. Petersburg branch of the All-Russian Society of Anatomists, Histologists, Embryologists, Pirogov Surgical Society, St. Petersburg Society of Naturalists.
On April 19, 2014, at St. Petersburg State University, in the building of the Twelve Collegiums, the All-Russian Medical and Biological Scientific Conference of Young Scientists with International Participation “Fundamental Science and Clinical Medicine” (XVII All-Russian Conference “Man and His Health”) was held, at which young scientists presented works dedicated to current fundamental and applied issues of experimental, clinical, preventive medicine and related biomedical sciences.
The conference was attended by more than 500 young researchers, from schoolchildren to associate professors, from 144 organizations in 75 cities of Russia, as well as Austria, Belarus, Germany, Kazakhstan, Kyrgyzstan, China, Moldova, the USA, Tajikistan, Ukraine, and Uzbekistan. At the conference itself, 36 oral reports were heard and more than 160 poster presentations were presented, in the ongoing publication Fundamental Science and Clinical Medicine - Man and His Health: Abstracts of the XVII All-Russian Medical and Biological Conference of Young Researchers (with international participation). – St. Petersburg: St. Petersburg State University Publishing House, 2014. - 564 p. [Fundam. science wedge. honey. - 2014. - T. 17. - P. 1–564] - 477 works by 758 young researchers and lectures by leading scientists were published.
At the end of the conference, the winners were awarded diplomas of various denominations in the categories of oral and poster presentations on clinical and medical-biological topics, as well as special prizes and diplomas from scientific and professional societies - the St. Petersburg branch of the International Society of Pathophysiologists (ISP), the Russian Physiological Society named after I. P. Pavlov, St. Petersburg City Palace of Youth Creativity, Elbi-SPb Publishing House, Bekhterev Psychiatric Society, St. Petersburg Branch of the All-Russian Society of Anatomists, Histologists, Embryologists, International Academy of Sciences Russian Section (Health and Ecology), Pirogov Surgical Society, St. Petersburg Society of Naturalists. The winners included young scientists from 12 cities and 33 different scientific and educational institutions Belarus, Germany, Kazakhstan, Russia and Ukraine, and St. Petersburg State University is represented among the winners by 3 faculties.
On April 20, 2013, at St. Petersburg State University, in the building of the Twelve Collegiums, the All-Russian Medical and Biological Scientific Conference of Young Scientists with International Participation “Fundamental Science and Clinical Medicine” (XVI All-Russian Conference “Man and His Health”) was held.
The conference was attended by more than 400 young researchers, from schoolchildren to associate professors, from 142 organizations in 63 cities of Russia, as well as Azerbaijan, Belarus, Germany, Georgia, Iraq, Iran, Kazakhstan, Kyrgyzstan, China, Latvia, Moldova, Mongolia, Pakistan, Tajikistan, Ukraine, Uzbekistan, Sweden. At the conference itself, 36 oral reports were heard and more than 120 poster presentations were presented, in the ongoing publication Fundamental Science and Clinical Medicine - Man and His Health: Abstracts of the XVI All-Russian Medical and Biological Conference of Young Researchers (with international participation). – St. Petersburg: St. Petersburg State University Publishing House, 2013. - 512 p. [Fundam. science wedge. honey. - 2012. - T. 16. - P. 1–512]. Abstracts of 430 works by 689 young researchers selected by reviewers were published. The works are devoted to current fundamental and applied issues of experimental, clinical, preventive medicine, as well as related biomedical sciences.
The All-Russian Medical and Biological Scientific Conference of Young Researchers "Fundamental Science and Clinical Medicine - Man and His Health" has been held at St. Petersburg State University annually since 1997. The conference brings together authors and participants from all over Russia and other countries. About 600 people participate in the conference every year. During the conference, sessions of oral and poster presentations on clinical and biomedical topics are held. As part of the conference, leading scientists traditionally give lectures to young scientists.
Schoolchildren, students, interns, residents, graduate students, and young researchers (under the age of 35) are invited to participate in the conference. Works on a wide range of problems of morphology, physiology, pathology, pharmacology, biophysics, biochemistry, genetics, and all branches of clinical and preventive medicine are accepted.
The purpose of the conference is to attract young researchers to solve pressing problems of modern science, to integrate higher education and fundamental science. Oral and poster presentations will be selected from the submitted works. Abstracts of the conference reports will be published in the ongoing publication of St. Petersburg State University “Fundamental Science and Clinical Medicine” (Fundam. Nauka Klin. Med.), ISSN 2221-5654.
Abstract map 201 3
Conference News:
On April 21, 2012, the XV Anniversary All-Russian Medical and Biological Conference of Young Researchers (with international participation) “Fundamental Science and Clinical Medicine. Man and his health."
The conference was attended by more than 570 young researchers, from schoolchildren to associate professors, from 100 organizations in 46 cities of Russia, as well as Belarus, Iran, China, Kazakhstan, Latvia, Moldova, Mongolia, Uzbekistan, Ukraine, South Ossetia. At the conference itself, 36 oral reports were heard and more than 70 poster presentations were presented; about 400 works were published in the collection of conference proceedings (Fundamental Science Clinical Med. – 2012. – vol. 15. – p. 1 – 412, ISSN 2221 - 5654) , selected by reviewers.
The jury members are representatives of the medical, dental, biology, soil and chemical faculties of St. Petersburg State University, as well as St. Petersburg State Medical University. acad. I.P. Pavlova, Vmeda im. CM. Kirov, St. Petersburg State Pedagogical Academy, five scientific and professional societies, the Palace of Youth Creativity, and the medical book publishing house "ElBi-SPb" - based on the results of the conference, 37 diplomas of various denominations were awarded in different categories. The winners included young researchers from Russia, Belarus, China, and Kazakhstan.
BASIC SCIENCE AND
CLINICAL MEDICINE
Tenth All-Russian
young researchers
"Man and his health"
Saint Petersburg
The Russian Academy of Sciences
Scientific Council of the Russian Academy of Sciences for Physiological Sciences
St. Petersburg Scientific Council on Problems
biology and medicine
Federal Agency of Education of the Russian Federation
St. Petersburg State University
Faculty of Medicine
Russian Physiological Society
them. I.P. Pavlova
St. Petersburg City Palace of Youth Creativity
FUNDAMENTAL
AND
CLINICAL MEDICINE
Tenth All-Russian
biomedical conference
young researchers
"Man and his health"
Saint Petersburg
Organising Committee
Chairman S.V. Petrov, Doctor of Medical Sciences, Professor
Deputy Chairman N.P. Veselkin, corresponding member. RAS
O.V. Fionik, Ph.D., Associate Professor
Members of the organizing committee E.K. Ailamazyan, Academician of the Russian Academy of Medical Sciences
Yu.V. Natochin, Academician of the Russian Academy of Sciences
N..N. Petrova, Doctor of Medical Sciences
Program Committee A.V. Balakhonov, Ph.D., Associate Professor
L.G. Magazanik, corresponding member. RAS
YES. Niauri, Doctor of Medical Sciences, Professor
A.G. Obrezan, Doctor of Medical Sciences, Professor
N.N. Petrova, Doctor of Medical Sciences
O.V. Fionik, Ph.D., Associate Professor P.K.
L.P. Churilov, Ph.D., Associate Professor
S.D. Sheyanov, Doctor of Medical Sciences, Professor
A.N. Shishkin, Doctor of Medical Sciences, Professor
M.V. Erman, Doctor of Medical Sciences, Professor
PC. Yablonsky, Doctor of Medical Sciences
Editorial board I.P. Mavidi, Ph.D.
E.R. Khalitova
RELATIONSHIP OF CLINICAL
AND CYTOGENETIC DISORDERS
IN CEREBRAL PALSY
D.V. Abdullatypova, class. hord.
Kazan State Medical University,
Department of Neurology, Neurosurgery with a course in medical genetics. Kazan, Russia
Objective: to study the relationship between clinical and cytogenetic disorders in cerebral palsy (CP).
Research material. 71 children with various forms of cerebral palsy and 40 healthy individuals were examined. The study included children with intact intelligence studying at a specialized boarding school for children with cerebral palsy. All patients were divided into clinical forms of the disease: hyperkinetic – 13 people. (18.3%), hemiparetic – 25 people. (35.2%) and spastic diplegia – 33 people. (46.5%).
Research methods: 1) clinical and neurological, including a score of the severity of 22 clinical indicators of movement disorders, each of which was scored from 0 to 5 points; 2) micronucleus test, with the study of 20,000 red blood cells in a peripheral blood smear from each patient and identifying the number of red blood cells with micronuclei (EM), expressed as a percentage; 3) statistical.
Results. A score assessment of the severity of clinical manifestations of cerebral palsy revealed that the most severe changes in self-care, motor deficits, sensory functions are significantly more often determined in children with the hyperkinetic form of cerebral palsy, compared with other forms (p The severity of the disease significantly prevailed in girls compared to boys, patients spastic diplegia, (r
The average values of EM in all forms of cerebral palsy significantly exceeded the spontaneous level of cytogenetic disorders in the control group 0.21% and 0.08%, respectively (p
The preliminary data obtained suggest that girls suffer more severely from cerebral palsy, whereas it is known that the disease is more common in boys. Sex differences are clearly visible in diseases of a multifactorial nature. Since with multifactorial inheritance the severity of the disease in the rarely affected sex is more severe, with a certain degree of probability cerebral palsy can be attributed to a pathology with polygenic inheritance. Of course, these proposals require additional research in this direction.
FEATURES OF PERFORMANCE OF SPECIFIED MOTOR ACTIONS WHEN LEFT-HANDERS AND RIGHT-HANDERS PERCEIVE FEEDBACK OF DIFFERENT CHARACTER
A.P. Abramova, student
Tver Gymnasium No. 44. Tver, Russia
Most human activities are associated with the perception and processing of information. Considering the presence of dominance of one of the hemispheres, a problem arises: what are the features of motor actions when perceiving verbal or formalized information in people with different leading hemispheres.
Purpose: to analyze the difference in the performance of precision movements when left-handers and right-handers perceive information feedback of a verbal and formal nature.
The study is based on the kinematometry method, which makes it possible to quantify muscle-joint sensitivity. The study included two series of experiments. First episode. Reproduction accuracy was recorded for left- and right-handers right forearm at a given angle of 45 degrees on a horizontal kinematometer. The position of the forearm is fixed at a given angle under visual control. Then the subject, with his eyes closed, reproduces the given angle 5 times under the following conditions: a) without informing the subject of the result of the action performed; b) with communication to the subject of the result of the completed action in verbal form, using words "more"- when the specified angle is exceeded, "less"- when not reaching the specified angle and "exactly"- when accurately reproducing a given angle; c) with communication to the subject of a specific (formalized) result of the action performed - for example, “42 degrees”. Second series The experiment included repetition of these experiments, but when reproduced by left-handers and right-handers with the movement left forearm at a given angle of 45 degrees.
The results of two series of experiments show that right-handers and left-handers are equally poor at performing precise movements based on proprioceptive information, and feedback in the form of a subjective sensation of muscle tension is insufficient to correct motor action. The presence of interhemispheric functional asymmetry of the sensory type determines the difference in the perception of verbal and formalized information feedback by left-handers and right-handers: when operating with the dominant hand, right-handers perceive verbal information better, and left-handers perceive formalized information better. The degree of formalization of feedback affects the accuracy of correction when performing given motor actions: the higher the level of formalization of feedback, the more accurate the subsequent action performed.
INFLUENCE OF SOME RISK FACTORS OF EARLY DYSONTOGENESIS ON MEMORY DEVELOPMENT IN HIGH SCHOOL STUDENTS
M.A. Abramova, student.
Pomeranian State University
them. M.V. Lomonosov, Faculty of Psychology, Department of Psychology. Arkhangelsk, Russia
The need to analyze the causes of possible deviations and organize individual correctional assistance for high school students during the period of their development is most relevant, because in early adolescence, important processes associated with the restructuring of memory occur (Leontyev A.N., 1931, Rean A.A., 2003). The purpose of our work is to identify the influence of risk factors for early dysontogenesis on memory development in children 15-16 years old.
During the scientific work, 24 people aged 15-16 years (12 boys and 12 girls) studying at secondary school No. 50 in Arkhangelsk and who did not have a history of severe neurological disorders were examined. At the first stage of the study, the most common risk factors for early dysontogenesis in high school students were identified using a questionnaire developed at the Research Institute of Age-Related Physiology of the Russian Academy of Education. At the second stage, methods were selected that made it possible to comprehensively assess the psychophysiological development of memory in an individual child: the “10 words” test (auditory short-term memory), the Bernstein test “9 geometric figures” (short-term visual memory), the method of reproducing differently perceived words ( leading type of memory).
A study of the level of psychophysiological development of children 15-16 years old indicates that the majority of high school students have a volume of short-term auditory (75.00±1.46% of children) and visual memory (83.33±1.54% of children) that corresponds to age standards. For the majority of adolescent children, the leading types of memory are combined (41.67±1.09) and visual (20.83±0.77).
A survey of parents of high school students revealed that 83.33±1.54% of children have risk factors in early development: toxicosis of the first half of pregnancy, maternal age, artificial feeding of the child from birth, taking medications during pregnancy, maternal morbidity during pregnancy .
High school students with a history of risk factors for early dysontogenesis have lower levels of memory development than children without risk factors. Thus, in the experimental group with a large number of risk factors in early development, the volume of short-term auditory and visual memory is 2 times less compared to children in the control group (50% and 100%, respectively).
Features of the influence of hypothermia on the force of contraction of the gopher's heart.
The role of calcium homeostasis
A.S. Averin, asp., E.V. Aleshkevich, student, S.V. Tarlachkov, stud.
Institute of Cell Biophysics RAS, Laboratory of Mechanisms of Natural Hypometabolic States. Pushchino, Russia
A serious medical and biological problem is the violation of the contractility of the heart during cooling. The myocardium of hibernating animals is a unique model for studying the mechanisms that ensure its functioning under conditions of a body temperature difference from 37 to 0 o C. This ability indicates a special plasticity of calcium homeostasis in the heart of hibernating animals, the mechanisms of which still remain unclear. The response of the force of contraction to a change in the frequency of stimulation (frequency-force relationship) and the introduction of a pause against the background of stimulation of the heart at a constant frequency (rhythmoinotropic relationships) are widely used to assess the contribution of various calcium transporting systems to the regulation of the force of contraction of cardiac cells. It has been shown that the nature of rhythminotropy largely depends on temperature. In this work, we investigated the influence of the temperature of the perfusion solution (from 37 to 4°C) on the frequency-force relationship (in the range from 0.1 to 1.0 Hz) and the pause effect in the heart of the ground squirrel in different functional states of animals (activity, hibernation, entering into hibernation, awakening). For the first time, 2 main types of reaction to a decrease in temperature in hibernating animals were discovered. In most active animals, when the temperature decreases from 30 to 5 o C, the frequency-force relationship turns from negative to positive, the force of contraction increases, and the potentiating effect of the pause disappears. In sleeping animals, the frequency-force relationship remains negative over the entire range of temperatures studied, the force of contraction decreases, and the potentiating effect of the pause is maintained and even intensified. A study of the dependence of rhythmoinotropic characteristics on extracellular calcium in combination with the use of blockers of various calcium transporting systems showed that in all studied groups of animals, the force of contraction at low temperatures (5 o C) significantly depends on extracellular calcium.
CHANGES IN ELECTROCARDIOGRAM INDICATORS AND HEART RATE VARIABILITY
EMERGENCY WORKERS
DURING THEIR PROFESSIONAL ACTIVITIES
K.A. Alekseev, student
Novgorod State University named after. Yaroslav the Wise,
Institute of Medical Education,
Department of Normal Physiology. Veliky Novgorod, Russia
Long-term motivational and emotional stress in people during the working day (including forms of professional stress among doctors and other medical workers) is expressed in “mental and physiological reactions to a wide range of situations in work activity” (V.A. Vinokur, O.V. Rybina., 2004). At the same time, it is observed known addiction: The harder a healthcare worker works, the more actively he or she avoids thoughts and feelings associated with occupational stress. In connection with the above, it was of interest to identify changes in the nature of the ECG and HRV (heart rate variability) among emergency station workers medical care during daily duty. The observations involved 25 people (10 men and 15 women) aged from 25 to 60 years with different levels of personality self-esteem. The study was carried out at the emergency medical station of the city of Pskov. To determine changes in the nature of the ECG and HRV, the method of 24-hour Holter monitoring was used, and for self-assessment of personality, the V.K. Gerbachevsky questionnaire was used. The main attention in the study was focused on identifying the “physiological price” of implementing the characteristics of the motivational spectrum of activity of the subjects during a work shift in terms of their cardiovascular functions. In general, when analyzing ECG and HRV indicators in subjects from 5 groups, 3 main variants of the dynamics of the motivational-emotional spectrum of activity and associated shifts in heart activity were identified. Option 1. Preservation of “voluntary-constructive” tendencies in production activities during the work shift. The appearance of single supraventricular extrasystoles was noted, and a decrease in the ST interval (no more than 2 mm) was detected. Option 2. Transition of “voluntarily - constructive” tendencies into “emotionally - reactive” ones. In the ECG subjects, changes were characterized by the appearance of a negative T wave. Option 3. Preservation of “emotionally reactive” tendencies in the process of current activity. Single supraventricular extrasystoles were recorded on the ECG. The data obtained indicate the high sensitivity and extreme diversity of the dynamics of the studied psychophysiological indicators in people in the process of performing their production activities.
Autoimmune reactions of lymphocytes in patients
with acute and chronic cerebral ischemia
E.V. Andrianova, class. order, A.A. Baytelieva, researcher,
T.V. Kim, student, M.V. Sotnikova, st.
Kyrgyz-Russian Slavic University, Faculty of Medicine, Department of Special Clinical Disciplines No. 2.
Institute of Molecular Biology. Bishkek, Kyrgyzstan
Autoimmune reactions to phospholipids are important in the mechanisms of vascular damage. Sensitization to them can contribute to the development of atherothrombosis. However, the state of cellular reactions to phospholipids and their diagnostic significance in cerebrovascular pathology remain poorly studied.
We examined patients with acute and chronic cerebrovascular insufficiency: ischemic stroke (IS) and dyscirculatory encephalopathy stages II and III (DE). Diagnoses of IS and DE were based on generally accepted criteria, in in doubtful cases Neuroimaging and cerebrospinal fluid examination were performed. The cytotoxic effect of sensitized lymphocytes (CTEL) was studied using the method of V.L. Morozov as modified by M.I. Kitaev.
A study of CTEL with cardiolipin in a group of patients with IS revealed its sharp increase compared to controls (p
The results of the study indicate that patients with cerebrovascular diseases develop cytotoxic reactions of lymphocytes with cardiolipin, and a clear dependence of the degree of change in the indicator on the severity, localization, and stage of the process is revealed.
REGULATION OF HUMAN IMMUNOGLOBULIN J-PEPTIDE EXPRESSION IN SQUAMOUS CELL CANCER AND LUNG ADENOCARCINOMA
N.V. Antipova, student.
IBCh RAS named after. M.M. Shemyakina and Yu.A. Ovchinnikova LSFGCh.
Moscow, Russia
Lung cancer is one of the most intensively studied tumors in recent years. This disease is one of the three most common forms of cancer, and it has a high mortality rate among patients, so markers are needed to diagnose it. In squamous cell lung cancer, increased expression of immune system proteins is observed, which may be due to the active penetration of B lymphocytes into the area of the malignant neoplasm and the presence there large quantity antigen presenting cells. The protein we are studying has an immunoglobulin type of polypeptide chain folding and consists of 159 amino acids in a single polymer with molecular weight 15 KDa. It has been shown that the level of expression of the J-peptide gene changes in various pathologies (mainly in pathologies affecting the lungs or gastrointestinal tract). For the study, tumor tissue samples were selected from the central and peripheral regions of the lungs at stages I-III of the disease and included highly and poorly differentiated forms of the tumor. In addition, the work used normal tissues from the central and peripheral parts of the lungs, taken from 5 patients without visible pulmonary pathologies. It was shown that with an increase in the number of patients studied with squamous cell carcinoma and lung adenocarcinoma, regardless of the area and stage of the disease, a predominantly reduced expression of J-peptide was observed in poorly differentiated forms of the tumor. The type of regulation of J-peptide synthesis was determined by the ratio of its content in the tumor to normal tissue (T/N) in each pair of samples. For 42% of the studied samples, a decrease in the J-peptide content in tumor tissues was observed, an increase for 27%, and for 31% no differences were found. For the group with central localization of a well-differentiated tumor, half of the N-T sample pairs showed no changes in J-peptide synthesis, and the remaining samples were equally distributed between the regulation variants. Based on these results, it can be assumed that the poorly differentiated form of the tumor is more regulated, and transformed cells in this case more easily perceive external metabolic signals, while the tumor containing highly differentiated cells is in an isolated, more stable state. Thus, from the presented results it follows that the translation of J-peptide in immunocytes depends on the state of the epithelium, the defeat of which by squamous cell carcinoma or lung adenocarcinoma leads to a predominantly reduced expression of this protein.
Changes in p53 and Bcl-2 immunoreactivity
in the paraventricular and supraoptic nuclei of the hypothalamus after sleep deprivation in rats
I.V. Artamokhina, student, V.A. Belova, st.
Institute of Evolutionary Physiology and Biochemistry
named after I.M. Sechenov RAS,
Laboratory of comparative somnology and neuroendocrinology.
Saint-Petersburg, Russia
It is known that the P53 and Bcl-2 proteins play an important role in the regulation of apoptosis in various tissues and, especially, during the morphogenesis of nervous tissue. However, the expression of these proteins in neurons of various parts of the brain and, especially in the hypothalamus, has been shown in adult animals, both normally and under various functional loads that did not cause neuronal death. A number of studies suggest that, in addition to the mechanisms of programmed cell death, P53 and Bcl-2 have great importance in the regulation of neuronal activity when their functional state changes. Sleep deprivation (interruption) is a generally accepted model for studying somnogenic brain structures, which causes a state of tension in various body systems. It is known that the hypothalamus and, in particular, the paraventricular (PVN) and supraoptic (SON) nuclei play an important role in the body’s adaptation to various stressors. In this regard, the purpose of the present study was to determine whether the expression of P53 and Bcl-2 in the PVN and SOF changes after 6 hours of sleep deprivation followed by 2 hours of sleep deprivation. In the experiment, 3 groups of male Wistar rats were used: control, after DS and after recoil. P53 and Bcl-2 were detected immunohistochemically on free-floating brain sections using specific unlabeled antibodies. A quantitative analysis of changes in the immunoreactivity of these proteins in the PVN and SOF was carried out, which revealed an increase in the number of P53- and Bcl-2-immunoreactive cells in both nuclei after SD and recoil. An increase in the optical density of P53 in the PVN was detected compared to the control by 83% (p 0.05) after SD and by 40% (p 0.05) after recoil; in SOY by 64% (p>0.05) after DS and by 78% (p RESULTS OF CREATION OF A BLADDER WITH PART OF THE STOMACH IN PATIENTS AFTER ITS REMOVAL
ABOUT CANCER
D.N. Atmadzhev, PhD candidate, A.V. Sergeev, associate, V.A. Fadeev, ass.,
O.A. Kirichenko, PhD candidate, M.V. Korokhodkina, PhD candidate, O.O. Burlaka, asp.
St. Petersburg State Medical Academy
them. I.I. Mechnikova, Department of Urology. Saint-Petersburg, Russia
Introduction: In 1954, Sinaiko E.S. announced replacement Bladder(MP) segment of the stomach. A consistently low urine pH level reduces the risk of urinary tract infection, which occurs in 30% of intestinal reservoirs, and as a result reduces the risk of stone formation. Also, resorption of ammonium chloride does not occur in the gastric reservoirs, thus, hyperchloremic acidosis, which is a frequent companion of intestinal reservoirs, does not occur.
Materials and methods: From 2001 to 2007 We performed 22 radical cystectomies (RC) and gastrocystoplasties (GCP). In 8 patients, we performed HCP in our own modifications (patent for invention No. 2204951 dated May 27, 2003). There were 16 men (72.7%), 6 women (27.3%). The age range of the patients was from 44 to 72 years. The average age was 61.6 years.
Results: There were no deaths in the early postoperative period. Of the 22 operated patients, 3 (13.6%) had complications associated with urinary diversion and accompanied by secondary pyelonephritis. In 2 patients, the uretero-reservoir anastomosis failed on one side. They performed PPNS with simultaneous revision and drainage of the urinary leak, and subsequently performed antegrade stenting of the ureter. In the long-term postoperative period, up to 4 years, 18 patients after RC were available for examination. Complications were observed in 4 (22.2%) people. All of them had hematuria-dysuria syndrome, and in 3 others a large segment of the stomach was taken (in our modification). One of these patients developed a lymphocele, the second had a stricture of the uretero-reservoir anastomosis with the development of VUN and secondary pyelonephritis, for which percutaneous puncture nephrostomy was performed. Vesicoureteral reflux was detected in one patient. Thus, satisfactory functional results were obtained in 14 (77.8%) patients.
Conclusions: When replacing the bladder with a segment of the stomach, satisfactory immediate and long-term results were obtained. Gastrocystoplasty is the method of choice for urinary diversion in patients with chronic renal failure and impaired urodynamics of the upper urinary tract.
NUCLEAR AND SCREEN FORMATIONS OF THE CORTICOMEDIAL GROUP OF THE ROSTRAL LEVEL OF THE ANTERIOR DIVISION OF THE AMYGDALA COMPLEX OF RATS WAG/Rij
A.V. Akhmadeev, senior researcher, I.R. Garipova, asp.
Department of Morphology and Physiology of Humans and Animals.
Ufa, Russia
The structural organization of the amygdala complex of the brain (MC, corpus amygdaloideum) is characterized by complexity, which is predetermined by the presence of a variety of principles of organization of the gray matter included in its composition. The key to understanding the cytoarchitectonic features of the MK is the teaching of Zavarzin (1986) about nuclear and screen centers nervous system. A detailed analysis of the functional morphology of the MC, which revealed the presence of a combination of nuclear and screen principles of organization of gray matter and the functional community of nuclear and paleocortical structures on its territory, allowed us to offer a new look at its structural and functional organization as the nuclear-paleocortical complex of the telencephalon (Kalimullina, 1991).
The term “anterior section” denotes the territory of the MC located at the level of the anterior cortical nucleus. In Wistar rats, the anterior section has two parts: rostral and caudal (Akmaev and Kalimullina, 1993). The rostral part of the anterior part of the MC is located at the level of the nucleus of the lateral olfactory tract, in which three layers are clearly visible. The corticomedial group of this section also includes the anterior amygdala region, the anterior cortical and central nuclei, and the anterior intercalary masses.
The purpose of this work was to study the representation of nuclear and screen centers by studying the cytoarchitectonic features of the structures of the rostral level of the anterior part of the MC of WAG/Rij rats. The work was carried out on 10 mature rats using highly informative frontal sections of the MC (Kalimullina and Kalkamanov, 1989) stained with cresyl violet.
The results of the analysis made it possible to classify the central core and intercalary masses as nuclear centers. The nucleus of the lateral olfactory tract has the characteristics of the screen center. The anterior cortical nucleus has the character of an interstitial formation. The anterior amygdala region, distinguished on the basis of the topographic principle, is a transitional formation.
POSTERMEDIAL NUCLEUS OF THE AMYGDALA COMPLEX OF THE BRAIN: SEX DIFFERENCES IN DENDROARCHITECTONICS OF RETICULAR NEURONS
A.V Akhmadeev, senior researcher
Bashkir State University, Faculty of Biology,
Department of Morphology and Physiology of Humans and Animals. Ufa, Russia
In the system of neuroendocrine regulation, which forms the basis for the integration of the body, a central place is occupied by steroids, and, above all, sex hormones. They are universal inducers of a wide range of processes, ranging from gene expression to the determining effect on the morphogenesis of its systems (Akmaev, 1979, Akmaev, Kalimullina, 1993, Ugryumov. 1999, Shalyapina et al., 1995, 2005, etc.). A striking example the latter is the so-called sexual differentiation of the brain (SBD), carried out by androgens in a certain (critical) period of early ontogenesis (Reznikov, 1982, 2004). On modern stage development of ideas about sexual differentiation of the brain Special attention focuses on the role of extrahypothalamic structures in this process. One of these structures in the telencephalon is the amygdala complex, which has powerful nerve connections with the hypothalamus.
The posterior medial nucleus (Mep) is topographically located between the dorsomedial and posterior cortical nuclei. It has been shown that its neurons respond to ovariectomy and orchidectomy by changing karyovolumetric parameters (Akmaev, Kalimullina, 1982) and on its territory, sex differences in the binding of alpha-bungarotoxin by neurons, which is a ligand of nicotinic acetylcholine receptors, have been found (Arimatsu, Seto, 1982). Whether the morphogenetic effect of androgen is realized in the posterior medial nucleus during the period of PDM remains unknown.
The studies were carried out on Wistar rats of both sexes at the age of six months with a body weight of 300-350. The neuronal organization of Mep was studied in preparations prepared using the Golgi method. The identification of neurons was carried out based on the classification of T.A. Leontovich (1978). Quantitative characteristics of reticular neurons were subjected to statistical processing using the Statistica 5.5 program. The analysis revealed the presence of greater total length dendrites (p=0.02), dendritic field area (p=0.03) and total length of terminal branches (p=0.01).
The work was carried out with the financial support of the Grant of the President of the Russian Federation MK-2542.2007.4.
gene polymorphism association nfatc4 with the development of myocardial hypertrophy in athletes
I.I. Akhmetov, asp., Yu.V. Shikhova, st.
St. Petersburg Research Institute physical culture, Saint Petersburg.
Transcription factors of the NFAT (nuclear factor of activated T-cell) family take part in the embryonic development of the cardiovascular system and also mediate hypertrophic signals in the myocardium. It has been shown that gene overexpression NFATC4 induces the development of myocardial hypertrophy in mice, while the absence of this gene is lethal for them. In the gene NFATC4
In humans, a structural Gly160Ala polymorphism was discovered, the functional role of which in the remodeling of the cardiovascular system in athletes remains unstudied. The purpose of the study was to identify the association of the Gly160Ala gene polymorphism NFATC4
with the development of left ventricular myocardial hypertrophy (LVMH) in athletes. The study involved 72 athletes (39 men, 33 women) specializing in rowing and all-around speed skating. The DNA of the subjects was isolated from epithelial cells of the oral cavity using alkaline extraction or the sorbent method. Genotyping was performed by restriction fragment length polymorphism analysis. Echocardiographic assessment of morpho-functional remodeling of the myocardium of athletes was carried out using an Aloka-3500 ultrasound scanner. In the total sample of athletes, the frequency NFATC4
The Ala allele accounted for 47.9%. Correlation analysis revealed a relationship in men NFATC4
Ala allele with a risk of developing LVMH: in carriers of the Ala/Ala genotype, the mass of the left ventricular myocardium was significantly greater than in carriers NFATC4
Gly allele (398 (77) g versus 328 (70) g; r=0.4, p=0.01). In addition, in men, the Ala allele was associated with higher body mass index values (Ala/Ala – 25.3 (1.3) kg/m2, Gly/Ala+Gly/Gly – 23.5 (1.9) kg/m2; r=0.44, p=0.005). Among women, no dependence of echocardiographic parameters on genotypes was found NFATC4.
Thus, Gly160Ala gene polymorphism NFATC4
is associated with remodeling of the cardiovascular system and body mass index in men involved in rowing and all-around speed skating.
The role of vascular endothelial growth factor gene polymorphism in the remodeling of the cardiovascular system of athletes
I.I. Akhmetov, asp., A.M. Khakimullina, asp.
St. Petersburg Research Institute of Physical Culture. Saint Petersburg.
Academy of Sports and Applied Martial Arts. Moscow, Russia
It has been established that performing systematic physical activity is accompanied by adaptive changes in the form of growth blood vessels myocardium. Individual differences the extent of such adaptive changes is determined by genetic factors that determine the hereditary predisposition to perform physical activity. Identification of genetic markers associated with the regulation of myocardial vascular growth is an important task in sports medicine and genetics for solving many issues related to the prevention of professional pathologies in athletes. One of the main factors directly influencing vascular growth is vascular endothelial growth factor (VEGF). Among the studied gene variations VEGF In humans, it is necessary to isolate the G-634C polymorphism. It is known that VEGF The C allele is expressed to a greater extent than the G allele and is associated with high values of aerobic endurance. In this regard, we assumed that VEGF The C allele is protective against the risk of developing severe left ventricular myocardial hypertrophy (LVMH), which limits cardiorespiratory endurance. The purpose of the study was to identify the association of the G-634C gene polymorphism VEGF with remodeling of the cardiovascular system of athletes. The study involved 38 men and 33 women (members of the main and youth national teams of the Russian Federation), specializing in rowing and all-around speed skating. The subjects' DNA was isolated from oral epithelial cells. Genotyping was performed by restriction fragment length polymorphism analysis. Echocardiographic assessment of morpho-functional remodeling of the myocardium of athletes was carried out using an Aloka-3500 ultrasound scanner. In accordance with the hypothesis, we discovered an association VEGF The C allele with the lowest LVMH indices in male speed skaters, which is confirmed by the differences between carriers of the GG and GC genotypes according to the left ventricular myocardial mass index (344 (27) g/m2 versus 281 (53) g/m2, p=0.025), according to the thickness of the interventricular septum (1.35 (0.05) cm versus 1.23 (0.17) cm, p=0.019) and the thickness of the posterior wall of the left ventricle (1.47 (0.15) cm versus 1.26 (0.12), p=0.019).
STATE OF PROLIFERATIVE ACTIVITY IN BREAST TISSUE IN WOMEN AT RISK OF BREAST CANCER AFTER OVARIECTOMY
E.N. Baylyuk, asp., I.N. Kostyuchek, asp., A.V. Nikolaev, stud.
St. Petersburg State University, Faculty of Medicine, Department of Obstetrics and Gynecology.
Research Institute of Obstetrics and Gynecology named after. BEFORE. Otta RAMS.
Saint-Petersburg, Russia
We examined 109 patients operated on for uterine fibroids aged 40 to 52 years (average age 47.4 ± 3.8). In the process of preoperative preparation, after surgery (after 9-12 months), all patients underwent a comprehensive examination of the mammary glands (MG): assessment of the 5-year risk of developing breast cancer (BC) using the Gale model; physical and radiation examination of the breast. In women with a 5-year risk of developing breast cancer ≥ 1.7 (n=95), regardless of the detection of nodules in the mammary gland, a multifocal trephine biopsy of the breast was performed under echographic control. Proliferative activity in breast tissue was assessed histologically and immunohistochemically by determining the expression of tissue markers Ki-67 and proliferating cell nuclear antigen (PCNA). A comparative analysis was carried out depending on the volume of surgical intervention: hysterectomy without appendages (n=35), with mono- and bilateral oophorectomy (n=18 and 42, respectively). In 95 of the examined women (87.2%), the 5-year risk of developing breast cancer, calculated using the Gale model, was 1.85 ± 0.13, and was comparable to the same risk indicator in patients with breast cancer (1.93 ± 0.17; p
FUNCTIONAL ASYMMETRIES
ARMWRESTLERS
S.A. Bakumenko, stud.
Kuban State University of Physical Culture, Sports and Tourism, Department of Physiology. Krasnodar, Russia
The study of the individual profile of functional asymmetry (IPA) allows us to find new ways to achieve high sports results. Special requirements for asymmetry of technique are imposed in arm wrestling.
47 armwrestling athletes were examined; at the age of 19-27 years, IPA was determined by the combination of the sides of dominance of motor and sensory functions according to the scheme: arm - leg - eye - ear. The asymmetry coefficient (in%) was calculated for each paired organ. The right hand was dominant in 63.8% of cases, the left - in 29.8%, ambidexterity - 6.4%. The right leading leg was noted in 53.2% of athletes, the left – in 40.4%, ambidexterity – in 6.4%. The dominant right and left eyes were typical for 85.1 and 14.9%, respectively; ambidexterity of vision was absent. The leading right ear was identified in 63.9%, the left ear in 34.0%, hearing ambidexterity in 2.1%.
IPA among armwrestlers is represented by 16 options out of 80 theoretically possible. The greatest variability was observed in the group of right-handed athletes (10 options). “Absolutely right-handed” accounted for 34.0%. In general, 44.7% of arm wrestlers had right motor asymmetry, and 51.1% had sensory asymmetry. Mixed phenotypes with cross motor asymmetry - leading right hand and left leg - occurred in 12.8% of cases, with cross sensory asymmetry - leading right eye and left ear - in 10.6%, left eye and right ear - in 4.3 %.
In the group of left-handed arm wrestlers, the variability of IPA was less (5 options). “Absolute left-handers” accounted for 4.3%. Left motor asymmetry was observed in 25.5% of athletes, sensory asymmetry in 6.4%. In 4.3% of cases, a tendency towards cross motor asymmetry with the left arm and leg ambidexterity was noted. Mixed phenotypes with cross sensory asymmetry - right eye and left ear - accounted for 12.8%.
The results of the study indicate the uniqueness of IPA in arm wrestlers. “Right-handed” athletes may have various variants of cross motor and sensory asymmetry, but “left-handed” athletes are characterized by unilateral “left” motor asymmetry - a combination of the left leading arm and leg. Sensory asymmetry is aimed at dominance of the right eye.
STUDIES OF ANTHROPOMETRIC PARAMETERS
STUDENTS OF DIFFERENT AGES
S.O. Balagurin, st.
Karelian State Pedagogical University,
Faculty of Physical Education, Department of Anatomy, Physiology and Hygiene with a course of OMZ. Petrozavodsk, Russia
The purpose of the work was to identify patterns of changes in anthropometric parameters of students in specialized educational institutions and comparing them with the values recommended for their age.
The research was carried out in the winter of 2006-2007. 40 boys in grades 5 and 6 of the Republican Cadet Boarding School in Petrozavodsk were examined. Each class has 20 people. The average age is 11.6±0.08 years - the youngest group, 12.7±0.08 years - the older group. Functional parameters were studied (standing height, sitting height, body weight, circumference chest, dynamometry, etc.) and calculated indicators and indices: Pigne, Erisman, proportionality, harmony, physique strength, etc.
Studies have shown that there are age differences in height, weight and other indicators. Thus, the strength of the hands of sixth-grade students was significantly higher: it amounted to right hand 15.4±0.4 kg for fifth graders versus 20.1±1.17 for sixth graders, and, respectively, for the left hand 13.6±0.6 (5 grades) and 18.3±1.1 (6 grades) kg. The age difference was 31.1% for the right hand and 34.9% for the left hand. It should also be noted that the spread of measured values was higher among sixth-graders compared to fifth-graders, which may indicate emerging differences in the bodies of adolescents of different ages in this indicator.
Disproportionately long legs, especially pronounced, in senior group, as well as the disproportionately different shift in hand strength and weight compared to changes in height can be indirectly explained by the fact that the body of students in the older group has entered the stage of puberty.
It is alarming that the students of both groups, on average, are defined as weak in terms of harmonious physique (48-49%), as well as in terms of strength of physique (Pigne index) - 38.8, 48.4 c.u.
In our opinion, in general, weight slightly deviating from average statistical data (excess weight), weak and inharmonious physique can be explained by insufficient physical activity. We think that improving results in these parameters can be achieved by increasing physical activity, possibly increasing study loads associated with physical activity, or at least reducing the number of hours spent in a sedentary, semi-immobile state.
AWARENESS OF THE POPULATION ABOUT THE MARKET OF MEDICAL SERVICES
S.A. Balokhina, associate, G.E. Teptin, stud.
St. Petersburg State Medical University
them. acad. I.P. Pavlova, Department of Public Health and Healthcare. Saint-Petersburg, Russia
One of the important problems that arose during the period of reform and development of market relations in healthcare is the lack and imperfection of awareness of the population (potential buyers) about the medical services market. Unfortunately, the State Guarantees Program for providing citizens Russian Federation free medical care includes, among other things, only the types and volumes of medical care provided free of charge without reference to a specific list of medical services (standards) provided in the event of a particular disease. This leads to the fact that a number of medical institutions (mainly state-owned) often make their own decisions on the procedure and list of medical services that can be provided to patients at on a paid basis. Moreover, despite the main regulatory document (Resolution of the Government of the Russian Federation of January 13, 1996 No. 27 “On approval of the rules for the provision of paid medical services to the population by medical institutions”) regulating this type of activity, they are provided in parallel with services that are free to the population.
Taking into account the above, we analyzed the opinions of patients who sought medical care at state and non-state clinics about the list of medical services provided on a paid basis. A total of 200 people were interviewed. The survey results showed that due to the inaccessibility of free medical care, a significant portion (59.7%) of respondents believe that most services should be paid. This figure was highest (57.1%) among respondents under the age of 20. Among those who believed that dentistry should be paid, people aged 20-30 predominated (37.5%); cosmetology – aged 31-45 years (45.2%). Those with a secondary education (62.5%), unmarried (50.0%), as well as those with an average monthly income of 10 to 30 thousand rubles were most positive about all medical services being paid for (22.7%).
Thus, the analysis showed the readiness of part of the population to seek paid medical care, which should be taken into account when implementing a targeted marketing strategy.
Formation of pediatric service
in Kyrgyzstan
A.M. Baltabaev, student.
Kyrgyz-Russian Slavic University,
Faculty of Medicine, Department of Public Health and Healthcare. Bishkek, Kyrgyzstan
In Kyrgyzstan, before the establishment Soviet power there were no medical facilities.
In 1924 Kyrgyzstan was transformed into the Kara-Kyrgyz Autonomous Region. Its regional department became the leading health care center. In February 1925, a subdepartment for the protection of motherhood and infancy was created under this department, which included a subdepartment for the protection of children's health, which was first headed by Z. F. Bedareva, and from July 20, 1925. - Z. F. Tukhomitskaya.
In September 1925, a maternity hospital with 20 beds was opened in the regional capital, then maternity wards with 5 beds each were opened at the Przhevalsk and Jalal-Abad hospitals. To serve the nomadic population in 1925. 4 mobile children's consultations were organized, where patients were registered and subsequently actively treated. Thus, there arose new form medical services for the population - medical examination of patients.
In 1926, under the People's Commissariat of Health of the Kyrgyz Autonomous Soviet Socialist Republic, an independent department for the protection of motherhood and infancy was opened, which began to work on organizing medical care for children of all ages. In 1926, the first children's preventive outpatient clinic began to function in the city of Frunze.
By 1928, there were 10 mobile children's clinics and a dairy kitchen in Kyrgyzstan. During this period, the network of institutions for the protection of motherhood, infancy and childhood developed significantly. In 1928, there were 8 children's clinics operating in the republic, 3 of them in rural areas. In 1932, the first independent children's hospital with 35 beds opened in the city of Frunze; by 1937, the bed capacity increased to 50. In 1936, thanks to the initiative of the talented health care organizer Kh.D. Yarullabekova, a district hospital was opened in the Ton district, which had a women’s and children’s clinic. In 1938, two children's sanatoriums for children were opened in the republic (in Cholpon-Ata and Chon-Saroy) school age and pioneers, in particular the Cholpon-Ata sanatorium with 100 beds on the shore of Lake Issyk-Kul for children with tuberculosis intoxication, bronchoadenitis, and tuberculosis of the lymphatic glands. One of the founders of the maternal and infant health service in Kyrgyzstan was the doctor I.A. Lazhenitsin. A.A. Pokrovsky, who arrived in Pishpek in 1924 from Saratov, can rightfully be considered the first pediatrician and organizer of the pediatric business in Kyrgyzstan. He began active work to provide medical care to children.
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